ABSTRACT: This study was carry out to examine saliva and cheek cells DNA extraction with the use of household chemicals. This study adopts the experimental research design where data collected are tested. Quantitative assessment was performed by measuring op...

ABSTRACT

The comparative bioavailabilities (bioequivalence) of five generic brands of paracetamol were compared in six (6) healthy male volunteers. The aim was to study whether the generic brands are bioequivalent to the standard brand.

The study was carried out following oral...

ABSTRACT

Comparative bioequivalence studies of six selected brands of ciprofloxacin tablets was successfully conducted. In-vitro quality control studies were carried out on six randomly selected brands of ciprofloxacin to establish identity, weight uniformity, friability, crushing stren...

ABSTRACT

This study was aimed at assessing the comparative bioavailability of six brands of ofloxacin marketed in Zaria.

Comparative bioavailability studies of six brands of ofloxacin marketed in Zaria was successfully conducted. Quality assessment was conducted on the randoml...

ABSTRACT

Comparison of the effects of a single oral dose of cimetidine and propantheline on the pharmacokinetics of paracetamol were studied with paracetamol (1g) administered alone, concurrently with cimetidine (400mg), delay (1 hour) with cimetidine (400mg), concurrently with paraceta...

ABSTRACT

The influence of Cimetidine (400 mg) and Diazepam (5 mg) on the pharmacokinetics of oral paracetamol (1000 mg) was studied and compared in eight (8) healthy human under two (2) protocols; concomitant and delayed administration of paracetamol. Subjects received one treatment at...

ABSTRACT

Comparison of the effects of cimetidine and methyldopa were studied in 5 phases: via phase I, ingestion of paracetamol 1g alone, phase II, administration of paracetamol 1g and cimetidine 400mg concurrently, phase III administration of cimetidine 400mg followed by paracetamol 1g...

ABSTRACT

The influence of cimetidine (400mg) and Tramadol (100mg) on the disposition of oral single dose (1g) Paracetamol was studied and compared in 8 healthy human volunteers under two protocols; concomitant and delayed paracetamol administration.

Subjects received one treat...

ABSTRACT

Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...

ABSTRACT

Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...

ABSTRACT

Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...

ABSTRACT

Ciprofloxacin is a flouroquinololone antibiotic that is commonly prescribed empirically in Nigeria due to its broad spectrum of activity. However, the drug product is illegally handled by drug hawkers that allow the drug to be exposed to some environmental forces which may affe...